GZMM anticorps (AA 64-206)

N° du produit ABIN7602212

Cet anticorps anti-GZMM est un anticorps Lapin Polyclonal détectant GZMM dans WB et ELISA. Adapté pour Souris.

Aperçu rapide pour GZMM anticorps (AA 64-206) (ABIN7602212)

Antigène: GZMM (Granzyme M (Lymphocyte Met-Ase 1) (GZMM))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GZMM est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-GZMM anticorps

Épitope: AA 64-206

Fonction: Anti-Granzyme M/GZMM Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Granzyme M/GZMM Antibody Picoband® (ABIN7602212). Tested in ELISA, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse Granzyme M/GZMM recombinant protein (Position: A64-D206).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Mouse
ELISA, 0.1-0.5 μg/mL, -
1. Pao, L. I., Sumaria, N., Kelly, J. M., van Dommelen, S., Cretney, E., Wallace, M. E., Anthony, D. A., Uldrich, A. P., Godfrey, D. I., Papadimitriou, J. M., Mullbacher, A., Degli-Esposti, M. A., Smyth, M. J. Functional analysis of granzyme M and its role in immunity to infection. J. Immun. 175: 3235-3243, 2005. 2. Pilat, D., Fink, T., Obermaier-Skrobanek, B., Zimmer, M., Wekerle, H., Lichter, P., Jenne, D. E. The human Met-ase gene (GZMM): structure, sequence, and close physical linkage to the serine protease gene cluster on 19p13.3. Genomics 24: 445-450, 1994.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur GZMM

Antigène: GZMM (Granzyme M (Lymphocyte Met-Ase 1) (GZMM))

Autre désignation: Gzmm

Sujet:

Synonyms: Neuropeptides B/W receptor type 1, G-protein coupled receptor 7, NPBWR1, GPR7

Tissue Specificity: Found in cerebellum and frontal cortex. Detected at high levels in hippocampus, amygdala and trachea, at moderate levels in fetal brain, pituitary gland and prostate. Not in caudate, accumbens, kidney or liver. Also detected at high levels in lung carcinoma.

Background: Granzyme M is a protein that in humans is encoded by the GZMM gene. Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M. Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 28 kDa

ID gène: 16904

UniProt: O08643